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The Availability Heuristic

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A heuristic is a general problem-solving framework (Tversky & Kahneman, 1974). You can think of these as mental shortcuts that are used to solve problems. Different types of heuristics are used in different types of situations, and the impulse to use a heuristic occurs when one of five conditions is met (Pratkanis, 1989):

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Related Experiment Video

Updated: Mar 18, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

[Not Available].

Olivier Tribut¹, Danièle Bentué-Ferrer¹, Marie-Clémence Verdier¹

¹Laboratoire de Pharmacologie Biologique, CHU Pontchaillou, Rennes, France.

Therapie

|July 10, 2016

Summary

Gabapentin, an anticonvulsant, treats epilepsy in patients over 12. Therapeutic drug monitoring for gabapentin may be useful due to absorption variability and renal considerations.

Area of Science:

Pharmacology
Clinical Pharmacy
Neuroscience

Context:

Gabapentin is a GABA analogue used for epilepsy treatment in adults and children over 12.
It can be used as monotherapy or adjunct therapy with other anticonvulsants.
Gabapentin does not interfere with other anticonvulsant medications.

Purpose:

To evaluate the utility of therapeutic drug monitoring (TDM) for gabapentin.
To identify factors influencing gabapentin plasma concentrations and TDM necessity.

Summary:

Interindividual pharmacokinetic variability and saturable absorption are key considerations for gabapentin.
Dosing adjustments are necessary for patients with renal insufficiency.
Clinical studies indicate typical gabapentin plasma concentrations range from 2 to 20 mg/L.

Keywords:

gabapentin gabapentine suivi thérapeutique pharmacologique therapeutic drug monitoring

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Impact:

Therapeutic drug monitoring for gabapentin is considered possibly useful.
Understanding pharmacokinetic variability aids in optimizing gabapentin therapy.
This information supports clinical decision-making for gabapentin treatment and monitoring.