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Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons
Published on: August 23, 2016
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Zika virus, a pathway to new challenges
Zubia Jamil1, Yasir Waheed2, Taimoor Zeb Durrani3
1Fauji Foundation Hospital, Rawalpindi 46000, Pakistan.
Asian Pacific Journal of Tropical Medicine
|July 10, 2016
Summary
The Zika virus outbreak, primarily spread by mosquitoes, has caused significant health issues like microcephaly and Guillain-Barre syndrome. There are no specific treatments, emphasizing prevention and preparedness for future epidemics.
Area of Science:
- Public Health
- Virology
- Epidemiology
Background:
- The current Zika virus outbreak is the largest recorded, with 1.4 million cases in Brazil alone.
- The World Health Organization declared it a public health emergency of international concern.
- Zika virus poses significant risks, particularly to infants, causing microcephaly and other severe pregnancy complications.
Purpose of the Study:
- To highlight the scale and impact of the ongoing Zika virus outbreak.
- To discuss the known and potential transmission routes of the Zika virus.
- To underscore the urgent need for prevention strategies and preparedness for future disease outbreaks.
Main Methods:
- Review of epidemiological data from the current Zika outbreak.
- Analysis of reported health complications associated with Zika virus infection.
- Examination of economic and public health impacts.
Main Results:
- Over 1.4 million Zika cases reported in Brazil, with 4000 infant microcephaly cases.
- Increased incidence of Guillain-Barre syndrome observed during the outbreak.
- Significant economic losses estimated at US$3.5 billion in Latin America and the Caribbean.
Conclusions:
- There is an urgent need to investigate all potential Zika virus transmission routes, including blood transfusion and body fluid contact.
- The lack of antiviral drugs or vaccines necessitates a strong focus on preventive measures.
- Global preparedness for emerging infectious diseases like Zika and Ebola is crucial for managing future health risks.

