Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Availability Heuristic

The Availability Heuristic

A heuristic is a general problem-solving framework (Tversky & Kahneman, 1974). You can think of these as mental shortcuts that are used to solve problems. Different types of heuristics are used in different types of situations, and the impulse to use a heuristic occurs when one of five conditions is met (Pratkanis, 1989):

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Favipiravir tissue distribution and inhibitory quotients in preclinical models: towards a pipeline for evidence-based antiviral repurposing.

The Journal of antimicrobial chemotherapy·2026

Same author

Biologics in Kidney Transplantation: Why and How Should We Personalize Their Dosage?

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy·2026

Same author

External Evaluation of Population Pharmacokinetic Models of Cabotegravir, During Its Oral and Intramuscular Administration in HIV-Infected Patients.

CPT: pharmacometrics & systems pharmacology·2026

Same author

Iohexol Clearance and Kidney Transplantation: Determinants of Its Variation in Living Kidney Donors One Year After Donation and Impact on Glomerular Filtration Rate Gain in Kidney Recipients.

Fundamental & clinical pharmacology·2026

Same author

Insights from a six-year hair drug analysis compendium in drug-facilitated crimes involving vulnerable population cases.

Journal of forensic sciences·2026

Same author

Insights from a 6-year hair drug analysis compendium in drug-facilitated sexual assault cases.

Journal of forensic sciences·2026

Same journal

Pharmacology of pruritus (pathophysiology, therapeutic targets).

Therapie·2026

Same journal

Barriers to prescribing methylphenidate for adults with ADHD: A qualitative study.

Therapie·2026

Same journal

[Self-medication and its factors amongst Navymen aboard surface ships of the French Navy at sea: A descriptive study].

Therapie·2026

Same journal

Subacute cutaneous lupus erythematosus induced by ticagrelor: Recurrence after rechallenge.

Therapie·2026

Same journal

Multiple HIV virological failures related to bictegravir-valproic acid interaction evidenced by therapeutic drug monitoring: A retrospective study.

Therapie·2026

Same journal

Indication-related misuse of oral fluoroquinolones in adults by general practitioners in France.

Therapie·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 18, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

[Not Available].

Caroline Solas¹, Maxime Paré¹, Sylvie Quaranta¹

¹Laboratoire de Pharmacocinétique et Toxicologie, Hôpital de La Timone, Marseille, France.

|July 10, 2016

Summary

This summary is machine-generated.

Therapeutic drug monitoring of ribavirin is recommended for chronic hepatitis C (HCV) treatment. Monitoring ribavirin levels optimizes sustained virologic response and manages anemia side effects.

Keywords:

level of evidence niveau de preuve ribavirin ribavirine suivi thérapeutique pharmacologique therapeutic drug monitoring

More Related Videos

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

Published on: November 1, 2012

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos

Published on: December 28, 2016

Related Experiment Videos

Last Updated: Mar 18, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

Published on: November 1, 2012

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos

A Submerged Filter Paper Sandwich for Long-term Ex Ovo Time-lapse Imaging of Early Chick Embryos

Published on: December 28, 2016

Area of Science:

Pharmacology
Hepatology
Infectious Diseases

Context:

Hepatitis C virus (HCV) infection is a global health concern.
Current standard treatment involves pegylated interferon alpha and ribavirin.
Ribavirin exhibits significant inter-individual pharmacokinetic variability, impacting treatment efficacy.

Purpose:

To evaluate pharmacokinetic-pharmacodynamic relationships of ribavirin in HCV-infected patients.
To determine the association between ribavirin exposure and sustained virologic response (SVR).
To assess the correlation between ribavirin concentration and hematologic toxicity, specifically anemia.

Summary:

Sustained virologic response (SVR) in HCV treatment is significantly associated with ribavirin concentration.
A trough concentration of 2-3 μg/ml at week 4 is proposed as a therapeutic target.
Higher ribavirin concentrations (>2 μg/ml) are linked to an increased risk of severe anemia.

Impact:

Therapeutic drug monitoring (TDM) of ribavirin can improve management of treatment response.
TDM aids in mitigating dose-dependent hematologic toxicity, such as anemia.
Evidence supports the recommendation of ribavirin TDM for optimizing HCV therapy.