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Related Experiment Video

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High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities
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[Not Available].

Amel Chaabane1, Karim Aouam1, Nadia Ben Fredj1

  • 1Laboratoire de Pharmacologie, Faculté de Médecine, Monastir, Tunisie.

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|July 10, 2016
PubMed
Summary

The H1N1 vaccines Focetria® and Panenza® are effective and well-tolerated in Tunisia. Both vaccines demonstrated high efficiency (93.6%) and were safe for diverse populations.

Keywords:
H1N1adverse effecteffet indésirableefficacitéefficiencygrippeinfluenzavaccinvaccine

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Area of Science:

  • Epidemiology
  • Vaccinology
  • Public Health

Context:

  • Tunisia faced the H1N1 influenza pandemic.
  • Two vaccines, Focetria® and Panenza®, were available.
  • A prospective study was conducted to assess their real-world performance.

Purpose:

  • To evaluate the effectiveness of Focetria® and Panenza® against H1N1.
  • To assess the safety and tolerability of these vaccines.
  • To analyze vaccine imputability for adverse events.

Summary:

  • A study of 601 vaccinated individuals showed 93.6% vaccine effectiveness.
  • Adverse effects were recorded in 32.4% of subjects, with Focetria® having more frequent events.
  • Neither vaccine type nor patient factors influenced flu occurrence; most side effects were transient.

Impact:

  • Confirms the high efficacy and good tolerability of Focetria® and Panenza® during the H1N1 pandemic in Tunisia.
  • Provides evidence for vaccine safety across different demographic and health profiles.
  • Informs public health strategies regarding influenza vaccination.