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Related Experiment Video

Updated: Mar 18, 2026

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

Published on: November 15, 2013

[Not Available].

Magalie Bandrant¹, Haleh Bagheri¹, Lise Cuzin²

¹Service de Pharmacologie Clinique, Centre Midi-Pyrénées de Pharmacovigilance, de Pharmacoépidémiologie et d'Informations sur le Médicament, Centre Hospitalier Universitaire, Faculté de Médecine, Toulouse, France.

|July 10, 2016

Summary

This summary is machine-generated.

Improved reporting of adverse drug reactions (ADRs) associated with antiretroviral drugs was observed. This system enhancement led to better data collection for patient safety and drug monitoring.

Keywords:

adverse effects anthetoviral drugs antirétroviraux effets indésirables pharmacovigilance

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Area of Science:

Pharmacovigilance
Infectious Diseases
Clinical Pharmacology

Context:

Established a dedicated system for collecting antiretroviral-induced adverse drug reactions (ADRs) in 1999.
Data collected from November 1999 to April 2003 at Toulouse University Hospital.
Involved a pharmacovigilance resident monitoring ADRs during medical consultations.

Purpose:

To enhance the systematic collection and analysis of adverse drug reactions (ADRs) linked to antiretroviral therapies.
To improve the understanding and management of side effects from HIV medications.
To establish a robust pharmacovigilance system for antiretroviral drugs.

Summary:

Collected 613 ADRs from 428 patients over the study period.
88.6% of reported ADRs were classified as non-serious.
Drug withdrawal was necessary in 57% of cases due to adverse events.

Impact:

Demonstrated a significant improvement in the reporting of antiretroviral drug-induced ADRs.
Highlights the effectiveness of a structured pharmacovigilance system.
Contributes to enhanced patient safety in antiretroviral therapy management.