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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

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Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
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Pulmonary Tuberculosis II01:28

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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
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Pulmonary Tuberculosis V01:28

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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
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Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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Related Experiment Video

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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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Tuberculosis in Older Adults.

Shobita Rajagopalan1

  • 1Los Angeles County Department of Public Health, 123 West Manchester Boulevard, Inglewood, CA 90301, USA; Charles R. Drew University of Medicine and Science, Los Angeles, CA, USA.

Clinics in Geriatric Medicine
|July 10, 2016
PubMed
Summary
This summary is machine-generated.

Tuberculosis (TB) in older adults presents unique challenges due to atypical symptoms and difficult diagnosis. This review covers epidemiology, diagnosis, and management of TB in the elderly to improve prevention strategies.

Keywords:
AgingInfectionLong-term careTuberculosis

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Area of Science:

  • Gerontology
  • Infectious Diseases
  • Public Health

Background:

  • Tuberculosis (TB) is a leading infectious cause of death globally.
  • Preventing and controlling TB in elderly populations is a significant public health challenge.
  • Clinical presentations of TB in older adults can be atypical, mimicking age-related conditions.

Purpose of the Study:

  • To review the epidemiology, pathogenesis, clinical characteristics, diagnosis, management, and prevention of Mycobacterium tuberculosis infection in aging adults.
  • To highlight the specific challenges associated with TB in the elderly population.
  • To provide a comprehensive overview for healthcare professionals managing TB in older individuals.

Main Methods:

  • Literature review of current global data on TB in the elderly.
  • Analysis of pathogenesis and clinical manifestations specific to aging adults.
  • Synthesis of diagnostic and management strategies, including adverse drug reactions.

Main Results:

  • TB in the elderly often presents with non-specific symptoms, complicating early diagnosis.
  • Older adults are at higher risk for adverse drug reactions during TB treatment.
  • Management requires careful consideration of comorbidities and physiological changes associated with aging.

Conclusions:

  • Effective TB control in aging populations necessitates tailored strategies addressing diagnostic complexities and treatment challenges.
  • Further research is needed to optimize TB prevention and care for community-dwelling and institutionalized older adults.
  • Early recognition and appropriate management are crucial to reduce TB morbidity and mortality in the elderly.