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Development of a cell viability assay to assess drug metabolite structure-toxicity relationships

Payal Rana1, Yvonne Will1, Sashi Nadanaciva2

  • 1Drug Safety Research & Development, Pfizer, Eastern Point Road, Groton, CT 06340, USA.

Bioorganic & Medicinal Chemistry Letters
|July 12, 2016
PubMed

Keywords:
Cytochrome P450Drug-induced toxicityMetabolic activationReactive metaboliteStructural alerts

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