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[Hemofiltration as kidney function replacement treatment in newborn infants].

C H Schröder, C M Potting, R S Severijnen

    Nederlands Tijdschrift Voor Geneeskunde
    |May 13, 1989
    PubMed
    Summary

    Continuous arteriovenous haemofiltration (CAVH) offers an alternative for newborns needing renal replacement therapy when peritoneal dialysis is not feasible. While effective for fluid and potassium removal, CAVH clears urea less efficiently than peritoneal dialysis.

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    Area of Science:

    • Pediatric Nephrology
    • Critical Care Medicine
    • Neonatal Intensive Care

    Background:

    • Peritoneal dialysis is the standard treatment for acute renal failure in infants.
    • Extensive abdominal surgery can preclude the use of peritoneal dialysis.
    • Hemodialysis presents significant challenges in the neonatal population.

    Observation:

    • This report details the use of continuous arteriovenous haemofiltration (CAVH) in two newborn infants.
    • CAVH was utilized as an alternative renal replacement therapy.
    • The newborns had conditions that made peritoneal dialysis impossible.

    Findings:

    • Continuous arteriovenous haemofiltration effectively removes excess fluid and potassium in newborns.
    • The clearance of catabolic products, such as urea, is less efficient with CAVH compared to peritoneal dialysis.

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  • CAVH provides a viable option for fluid and electrolyte management in critically ill neonates.

    • Implications:

    • CAVH serves as a crucial alternative renal support method for neonates when conventional dialysis is contraindicated.
    • Further research may optimize CAVH protocols for improved solute clearance in infants.
    • This approach expands therapeutic options for neonatal acute kidney injury management.