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The fate of hips that are conservatively treated in multiple epiphyseal dysplasia
Seung-Ju Kim1, Ashok K Ramanathan, Young-Sik Jeon
1aDepartment of Orthopaedics, Hanil General Hospital bDepartment of Orthopaedic Surgery, Korea University Medical Center, Institute for Rare Diseases, Guro Hospital, Seoul, Korea.
Insights
Conservative treatment shows favorable midterm outcomes for hip deformity in multiple epiphyseal dysplasia (MED). Radiologic measurements improved, and Harris hip scores increased, indicating positive results for hip joints in MED patients.
Area of Science:
- Orthopedics
- Pediatric Orthopedics
- Radiology
Background:
- Multiple epiphyseal dysplasia (MED) is a rare genetic disorder affecting bone development, particularly in the hips.
- Hip joint involvement in MED can lead to deformity and affect long-term function.
- Conservative management strategies are often considered for pediatric hip conditions.
Purpose of the Study:
- To evaluate the radiologic and clinical outcomes of conservative treatment for hip deformity in patients with multiple epiphyseal dysplasia.
- To assess changes in key hip joint parameters over time with non-surgical management.
Main Methods:
- Retrospective review of 40 patients diagnosed with multiple epiphyseal dysplasia.
- Analysis of radiologic parameters including center-edge angle, femoral head coverage, acetabular angle, and acetabular depth index.
- Clinical assessment using Harris hip scores.
- Average follow-up duration of 7.2 years.
Main Results:
- Conservative treatment led to significant improvements in Harris hip scores (P=0.003).
- Radiologic measurements showed a tendency for increased center-edge angle and femoral head coverage (P=0.011, P=0.015).
- Statistically significant differences were observed in acetabular angle and acetabular depth index between initial visits and follow-up (P=0.046, P=0.027).
Conclusions:
- Conservative treatment offers favorable midterm outcomes for hip deformity in multiple epiphyseal dysplasia.
- Non-surgical management can lead to positive radiologic and functional improvements in affected pediatric hip joints.
Abstract:
We reviewed the radiologic and clinical outcomes of hip joints affected by multiple epiphyseal dysplasia in 40 patients. The average patient age was 9.6 years. All patients were followed up for an average of 7.2 years. No patient underwent surgical treatment. The variances of the center-edge angle and femoral head coverage had the greatest tendency to increase with conservative treatment and follow-up (P=0.011 and 0.015, respectively). The acetabular angle and the acetabular depth index at the first visit and the latest follow-up were statistically significantly different (P=0.046 and 0.027, respectively). According to the Stulberg classification, the severity of hip deformity became less severe with age, but this was not statistically significant (P=0.090). Larger improvements in Harris hip scores were identified after conservative treatment (P=0.003). Favorable midterm outcomes were obtained for the treatment of hip deformity in multiple epiphyseal dysplasia patients by conservative treatment.
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