Related Experiment Video

Updated: Mar 18, 2026

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn
11:27

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn

Published on: April 7, 2023

7.7K

Cardiopulmonary resuscitation in hospitalized infants

Christoph P Hornik1, Eric M Graham2, Kevin Hill1

  • 1Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA.

Early Human Development
|July 12, 2016
PubMed

Insights

Mortality after cardiopulmonary resuscitation (CPR) in hospitalized infants is high, especially for premature or younger infants with congenital anomalies. Identifying high-risk infants is crucial for improving survival rates.

Area of Science:

  • Neonatal intensive care
  • Pediatric critical care
  • Cardiopulmonary resuscitation research

Background:

  • Hospitalized infants undergoing cardiopulmonary resuscitation (CPR) are a vulnerable population.
  • Limited recent data exist on factors influencing survival after CPR in neonates.

Purpose of the Study:

  • To identify demographic characteristics, diagnoses, and cardiopulmonary support levels associated with survival to hospital discharge after CPR in infants.
  • To analyze risk factors for mortality in infants requiring CPR.

Main Methods:

  • A retrospective cohort study was conducted using data from 348 neonatal intensive care units.
  • Infants aged 2 to 120 days receiving CPR between 1997 and 2012 were included.
  • Multivariable logistic regression analyzed predictors of death after CPR, accounting for center clustering.

Main Results:

  • The study included 2231 infants; 51% survived to discharge.
  • Lower gestational age, postnatal age, 5-minute APGAR scores, congenital anomalies, and illness severity markers predicted higher mortality.
  • Mortality rates following CPR did not significantly change over the study period.

Conclusions:

  • Infant mortality after CPR remains high, particularly for premature infants, those with congenital anomalies, and those requiring prior cardiopulmonary support.
  • Focusing on high-risk infant populations may reveal targets for CPR prevention strategies and outcome improvement.
  • Further research is needed to refine interventions for this critical patient group.
Abstract

Keywords:
Cardiopulmonary resuscitationInfantsNeonatal intensive care unitsSurvival

More Related Videos

A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation10:55

A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation

Published on: January 13, 2023

2.4K
Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine05:36

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine

Published on: January 30, 2020

8.6K

Related Concept Videos

Cardiopulmonary Resuscitation I: Adult01:21

Cardiopulmonary Resuscitation I: Adult

Cardiopulmonary resuscitation, or CPR, is a life-saving emergency procedure performed when a person's heart has stopped beating or they are no longer breathing. The foundation of CPR is Basic Life Support (BLS), which focuses on the early recognition of cardiac arrest, the immediate start of high-quality chest compressions, and the timely use of an automated external defibrillator (AED).Assessing Responsiveness and Checking the Carotid PulseWhen approaching an unresponsive person, first ensure...
965
Cardiopulmonary Resuscitation IV: Pharmacological Management01:25

Cardiopulmonary Resuscitation IV: Pharmacological Management

Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
1.2K
Cardiopulmonary Resuscitation III: AED Use01:23

Cardiopulmonary Resuscitation III: AED Use

Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...
1.1K
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
927
Respiratory Assessment: Purpose and Indications01:19

Respiratory Assessment: Purpose and Indications

Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
2.0K
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
744