Related Experiment Video
Updated: Mar 18, 2026
05:54
Author Spotlight: Non-Invasive Imaging of Complex Bio-Structures Using Polarization-Sensitive Two-Photon Microscopy
Published on: September 8, 2023
2.0K
Circularly-Polarized Luminescence (CPL) from Chiral AIE Molecules and Macrostructures
Jesse Roose1,2, Ben Zhong Tang1,2,3, Kam Sing Wong4
1HKUST-Shenzhen Research Institute, Hi-Tech Park, Nanshan, Shenzhen, 518057, China.
Small (Weinheim an Der Bergstrasse, Germany)
|July 12, 2016
Summary
Chiral fluorophores exhibiting circularly-polarized luminescence (CPL) and aggregation-induced emission (AIE) are crucial for advanced devices. This review summarizes design principles for creating these CPL-active AIEgens.
Area of Science:
- Materials Science
- Organic Chemistry
- Photophysics
Background:
- Circularly-polarized luminescence (CPL) is gaining traction for applications in chiral devices and biological probes.
- These applications necessitate chiral fluorophores with strong fluorescence in aggregated states.
- A new research area focuses on developing CPL-active fluorophores that are emissive when aggregated.
Purpose of the Study:
- To summarize early design principles for creating CPL-active and aggregation-induced emission (AIE) active fluorophores (AIEgens).
- To highlight successful strategies for achieving CPL and AIE properties simultaneously.
Main Methods:
- Review of existing literature on CPL-active AIEgens.
- Analysis of design strategies involving chiral alignment of monomeric emitters.
- Examination of approaches for individual CPL-active AIEgen synthesis.
Main Results:
- Alignment of monomeric emitters in a chiral fashion within supramolecules, polymers, or liquid crystals is a proven strategy.
- Initial reports demonstrate methods for synthesizing individual CPL-active AIEgens.
Conclusions:
- Combining CPL properties with AIE phenomena is a rapidly developing field.
- Chiral alignment strategies are effective for developing CPL-active AIEgens.
- Further research is advancing the synthesis of individual CPL-active AIEgens.
Related Concept Videos
02:30Chirality in Nature
17.8K
Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid.
17.8K
02:25Molecules with Multiple Chiral Centers
16.2K
Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
16.2K
01:26Variables Affecting Phosphorescence and Fluorescence
1.8K
Fluorescence and phosphorescence are essential phenomena in fields like analytical chemistry, biological imaging, and materials science, where they detect molecular properties and visualize cellular structures. Understanding the variables that influence these luminescent behaviors is crucial for maximizing accuracy and efficiency in their applications. These variables can broadly be grouped into chemical structure, solvent properties, and external conditions, each playing a distinct role in...
1.8K