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Related Experiment Video

Updated: Mar 18, 2026

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180&#176; Curved Artery Test Section
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[Study on Indicator Densitometry Determination Method of Hemodynamic Parameters].

Guang-da Liu, Run-dong Zhou, Yu-tong Zha

    Guang Pu Xue Yu Guang Pu Fen Xi = Guang Pu
    |July 13, 2016
    PubMed
    Summary
    This summary is machine-generated.

    A novel noninvasive method using near-infrared spectroscopy (NIRS) and indicator dilution accurately measures hemodynamic parameters like cardiac output. This technique offers a repeatable solution for clinical assessment, overcoming limitations of invasive methods.

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    Area of Science:

    • Biomedical Engineering
    • Medical Physics

    Background:

    • Clinical measurement of hemodynamic parameters is crucial but often invasive and complex.
    • Existing methods limit repeated measurements and patient comfort.

    Purpose of the Study:

    • To develop a noninvasive method for measuring hemodynamic parameters.
    • To address the limitations of current invasive clinical techniques.

    Main Methods:

    • Utilized near-infrared spectroscopy (NIRS) and indicator dilution theory.
    • Employed indocyanine green (ICG) as a tracer, analyzing its concentration via light transmission through the fingertip.
    • Calculated cardiac output (CO) and circulating blood volume (CBV) from ICG concentration curves.

    Main Results:

    • Achieved maximum relative errors of 8.88% for CO and 4.28% for CBV.
    • Maintained average relative errors below 5% compared to "gold standard" methods.
    • Demonstrated the method's clinical accuracy and suitability for repeated measurements.

    Conclusions:

    • The NIRS-based indicator densitometry method provides accurate, noninvasive hemodynamic parameter measurement.
    • This technique is a viable, repeatable alternative for clinical applications.
    • Overcomes invasiveness and operational complexity of traditional methods.