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Genome Editing in Mammalian Cell Lines using CRISPR-Cas
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On the Origin of CRISPR-Cas Technology: From Prokaryotes to Mammals

Francisco J M Mojica1, Lluis Montoliu2

  • 1Departamento de Fisiología, Genética y Microbiología, Universidad de Alicante, Alicante, Spain; Instituto Multidisciplinar para el Estudio del Medio, Universidad de Alicante, Alicante, Spain.

Trends in Microbiology
|July 13, 2016
PubMed

Keywords:
gene disruptiongene replacementgene therapygenetic modificationgenome-editing nucleaseshomologous recombinationmolecular biologygenetic engineeringprokaryotic immunitybiotechnology history

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