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Updated: Mar 18, 2026
Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
Published on: March 6, 2018
Arsenic exposure and risk of preeclampsia in a Mexican mestizo population
Ada Sandoval-Carrillo1, Edna M Méndez-Hernández2, Elizabeth I Antuna-Salcido1
1Institute of Scientific Research, Juarez University of the State of Durango, Av. Universidad y Fanny Anitua s/n. Col. Centro, C.P. 34000, Durango, Dgo, Mexico.
Background:
Exposure to arsenic in drinking water has been associated with various complications of pregnancy including fetal loss, low birth weight, anemia, gestational diabetes and spontaneous abortion. However, to date, there are no studies evaluating its possible association with preeclampsia.
Methods:
This case-control study involved 104 preeclamptic and 202 healthy pregnant women. The concentrations of arsenic in drinking water and urine were measured using a Microwave Plasma-Atomic Emission Spectrometer.
Results:
We found relatively low levels of arsenic in household tap water (range of 2.48-76.02 μg/L) and in the urine of the participants (7.1 μg/L vs 6.78 μg/L in cases and controls, respectively).
Conclusions:
The analysis between groups showed for the first time that at these lower levels of exposure there is no association with preeclampsia.
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