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Updated: Aug 19, 2026

Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
Published on: December 18, 2010
[Immunochemical properties of two natural forms of pituitary porcine prolactin]
Abstract:
A comparative analysis of immunological properties of previously isolated and structurally characterized glycosylated porcine prolactin was performed. Immunoelectrophoresis with antisera to nonmodified and glycolysated hormones revealed no qualitative differences in their immunological properties. Two radioimmunoassay systems for glycosylated and nonglycosylated prolactin were developed on the basis of these antisera. Glycosylated prolactin in both systems was shown to possess decreased immunoreactivity making up 40-50% of nonmodified prolactin activity.
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