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Macrophage Inflammatory Protein-1 Alpha: A Paradox?

A N Parker1, I B Pragnell2

  • 1a Dept Haematology , Western Infirmary , Dumbarton Rd, Glasgow G11 6NT , Scotland.

Hematology (Amsterdam, Netherlands)
|July 14, 2016
PubMed
Summary

Macrophage inflammatory protein-1 alpha (MIP-1α) is a pro-inflammatory C-X-C chemokine. This protein inhibits hematopoietic progenitor cell proliferation but can reduce stem cell loss and improve neutrophil recovery following cancer treatments.

Keywords:
MIP-1alphachemokinestem cell inhibition

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