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Updated: Mar 18, 2026

Author Spotlight: Exploring Glial Influence in Experience-Dependent Synaptic Pruning During Critical Periods
Published on: March 1, 2024
Developmental plasticity evolved according to specialist-generalist trade-offs in experimental populations of
Jacqueline Le Vinh Thuy1, John M VandenBrooks2, Michael J Angilletta3
1School of Molecular Sciences, Arizona State University, Tempe, AZ 85287, USA.
Abstract:
We studied the evolution of developmental plasticity in populations of Drosophila melanogaster that evolved at either constant or fluctuating temperatures. Consistent with theory, genotypes that evolved at a constant 16°C or 25°C performed best when raised and tested at that temperature. Genotypes that evolved at fluctuating temperatures performed well at either temperature, but only when raised and tested at the same temperature. Our results confirm evolutionary patterns predicted by theory, including a loss of plasticity and a benefit of specialization in constant environments.
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