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Updated: Mar 18, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
[Venous ulcer]
1Universitätsklinik für Dermatologie, Medizinische Universität Wien, Währinger Gürtel 18-20, 1090, Wien, Österreich. kornelia.boehler@meduniwien.ac.at.
Insights
Venous ulcers, a common issue, stem from increased venous pressure. Effective treatment involves addressing the venous disorder, wound care, and compression therapy to prevent recurrence.
Area of Science:
- Vascular Medicine
- Dermatology
- Wound Care
Background:
- Venous disorders are the primary cause of lower extremity ulcers, affecting 1% of the general population and 4% of the elderly.
- The chronic nature of these ulcers significantly impacts healthcare budgets, consuming 1% of Western healthcare spending.
- Accurate diagnosis of the underlying venous condition is crucial for effective, individualized treatment.
Purpose of the Study:
- To outline the essential components of managing chronic venous ulcers.
- To emphasize the importance of a comprehensive diagnostic approach.
- To highlight effective therapeutic strategies for venous ulcer treatment and prevention.
Main Methods:
- Investigating the underlying venous disorder causing increased venous pressure.
- Implementing therapies focused on eliminating venous reflux.
- Utilizing local wound management techniques, including shave therapy and split skin grafting.
- Employing compression therapy for both treatment and recurrence prevention.
Main Results:
- Chronic venous ulcers can be successfully treated with a combination of surgical interventions and wound care.
- Compression therapy plays a vital role in the successful management and long-term prevention of venous ulcer recurrence.
- Differential diagnoses, including arterial ulcers, vasculitis, and neoplasms, must be considered.
Conclusions:
- A thorough investigation of the venous disorder is fundamental for successful venous ulcer treatment.
- Integrated therapeutic approaches combining reflux elimination, wound management, and compression therapy yield optimal outcomes.
- Compression therapy is indispensable for both healing and preventing the recurrence of chronic venous ulcers.
Abstract:
Venous disorders causing a permanent increase in venous pressure are by far the most frequent reason for ulcers of the lower extremity. With a prevalence of 1 % in the general population rising to 4 % in the elderly over 80 and its chronic character, 1 % of healthcare budgets of the western world are spent on treatment of venous ulcers. A thorough investigation of the underlying venous disorder is the prerequisite for a differenciated therapy. This should comprise elimination of venous reflux as well as local wound management. Chronic ulcers can successfully be treated by shave therapy and split skin grafting. Compression therapy is a basic measure not only in venous ulcer treatment but also in prevention of ulcer recurrence. Differential diagnosis which have to be considered are arterial ulcers, vasculitis and neoplasms.
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