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Updated: Mar 18, 2026

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
Published on: September 12, 2025
[Uterine necrosis upon acute caesarean section in a homozygous factor VLeiden patient]
Peter Søndergaard Thyrrestrup1, Charlotte Brix Andersson, Søren Kjærgaard
1sondergaardp@gmail.com.
Peripartum hysterectomy is a rare but life-saving procedure. Haemorrhage, atony, placenta accreta/praevia or uterus rupture are the most common reasons for hysterectomy. This case report presents a 35-year-old woman, gravida 2, para 1, with total necrosis of the uterus and ovaries bilaterally after an acute caesarean section. Pathological examination showed thrombosis and haemorrhagic infarction. Besides pre-eclampsia the patient had no co-morbidity. Later analysis found homozygosity for factor VLeiden mutation. Hysterectomy was life-saving but the patient developed acute renal failure with late recovery.
Peripartum hysterectomy is a rare but life-saving procedure. Haemorrhage, atony, placenta accreta/praevia or uterus rupture are the most common reasons for hysterectomy. This case report presents a 35-year-old woman, gravida 2, para 1, with total necrosis of the uterus and ovaries bilaterally after an acute caesarean section. Pathological examination showed thrombosis and haemorrhagic infarction. Besides pre-eclampsia the patient had no co-morbidity. Later analysis found homozygosity for factor VLeiden mutation. Hysterectomy was life-saving but the patient developed acute renal failure with late recovery.

