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Misoprostol as aid in First Trimester MTP.
Shakti Vardhan1, R C Behera2, G S Sandhu1
1Associate Professor (Obstetrics and Gynaecology), AFMC, Pune-40.
Medical Journal, Armed Forces India
|July 14, 2016
Summary
Intravaginal misoprostol effectively ripens the cervix before first-trimester Medical Termination of Pregnancy (MTP). This method reduced the need for cervical dilatation in most cases, simplifying the procedure.
Area of Science:
- Obstetrics and Gynecology
- Reproductive Medicine
- Pharmacological Interventions
Background:
- First-trimester Medical Termination of Pregnancy (MTP) is common.
- Traditional Dilatation and Evacuation (D&E) requires cervical dilatation with metal dilators, often needing anesthesia and risking cervical trauma or incompetence.
- Intravaginal misoprostol offers a potential solution to avoid rapid cervical dilatation.
Purpose of the Study:
- To evaluate the efficacy of intravaginal misoprostol as a pre-MTP cervical priming agent.
- To assess the impact of misoprostol on the need for mechanical cervical dilatation during first-trimester MTP.
Main Methods:
- A 200-microgram intravaginal misoprostol tablet was administered the night before MTP.
- Cervical ripening was assessed, with mechanical dilatation used only if the cervix remained insufficiently dilated.
- Products of conception were removed via suction.
Main Results:
- Cervical dilatation was not required in 96 out of 108 cases (88.9%).
- The use of intravaginal misoprostol significantly reduced the need for mechanical cervical dilatation.
Conclusions:
- Intravaginal misoprostol (200 mcg) is an effective priming agent for first-trimester MTP.
- This method simplifies MTP procedures by facilitating cervical ripening and reducing the need for invasive dilatation.