Related Experiment Video
Updated: Mar 18, 2026

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
Published on: January 7, 2018
Diabetes Mellitus in India: The Modern Scourge
S R Mehta1, A S Kashyap2, S Das3
1Commandant, AMC Centre & School, Lucknow 226 002.
Diabetes in India is rapidly increasing, affecting urban adults a decade earlier than in the West. Early screening and lifestyle interventions like "Eat less, Eat on time, Walk more" are crucial for prevention.
Area of Science:
- Endocrinology
- Public Health
- Epidemiology
Background:
- India faces a rapidly escalating diabetes mellitus prevalence, projected to double by 2030.
- Urban Indian adults exhibit a 12.1% diabetes prevalence, with onset a decade earlier than Western populations.
- Type 2 diabetes is 4-6 times more prevalent in urban than rural India, influenced by familial aggregation, obesity, and urbanization.
Purpose of the Study:
- To highlight the escalating diabetes crisis in India.
- To identify unique risk factors and complications prevalent among Indian diabetic populations.
- To emphasize the importance of early screening and intervention strategies.
Main Methods:
- Review of existing studies on diabetes prevalence and risk factors in India.
- Analysis of demographic and clinical data related to diabetes and its complications.
- Identification of key preventative measures and screening protocols.
Main Results:
- Indians experience earlier diabetes onset and higher rates of Type 2 diabetes, particularly in urban areas.
- Increased prevalence of macro/microvascular complications and familial clustering of diabetic nephropathy in Indian diabetics.
- Syndrome X is common among urban Indians, indicating a high cardiovascular risk.
Conclusions:
- Urgent, effective interventions and timely screening are imperative to manage the growing diabetes burden and its complications in India.
- Screening for gestational diabetes is vital for primary prevention in mothers and children.
- Lifestyle modifications, including dietary changes and increased physical activity, are key to preventing diabetes onset and progression.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes: Symptoms, Diagnosis, and Complications
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

