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Updated: Mar 18, 2026

Assessment of the Metabolic Profile of Primary Leukemia Cells
Published on: November 21, 2018
Leukemia in Patients with Klinefelter Syndrome: A Report of Two Cases
M Bchir1, W Ayed2, H Ben Neji1
1Department of Hematology, Aziza Othmana University Hospital, Place du gouvernement, la Kasbbah, 1008 Tunis, Tunisia.
Abstract:
Klinefelter syndrome (KS) is a chromosome abnormality characterized by a 47, XXY karyotype associated with hypogonadism and infertility. We present two cases of leukemia in patients with KS. The first patient presented with acute promyelocytic leukemia. He relapsed after the end of treatment. The second patient was diagnosed with chronic myeloid leukemia. Treatment with imatinib failed and the patient presented with myeloid blast crisis.
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