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Aggressive Lymphomas Diagnosed in the Bone Marrow: Two Illustrative Cases
Rekha Bhat1, Swati Pai2, Kunal Das3
1Department of Laboratory Medicine, Manipal Hospital, 98 Rustom Bagh, Old Airport Road, Bengaluru, 560017 India.
Summary
Bone marrow examinations are crucial for diagnosing aggressive lymphomas, especially when subtle patterns are present. These exams can reveal lymphoma in the absence of other tissue samples, aiding early detection and treatment.
Area of Science:
- Hematology
- Oncology
- Pathology
Background:
- Lymphomas can present with subtle bone marrow involvement, posing diagnostic challenges.
- A high index of suspicion is often required for early detection.
Observation:
- Two patients with aggressive lymphomas presented with cytopenias.
- Bone marrow examinations were performed for both patients.
Findings:
- Bone marrow examinations revealed surprising results in both cases.
- These findings were crucial for diagnosing lymphoma in the absence of nodal or other tissue specimens.
Implications:
- Bone marrow examination is a valuable tool for diagnosing lymphomas, particularly when other diagnostic specimens are unavailable.
- This highlights the importance of considering bone marrow biopsy in unexplained cytopenias.
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