Related Experiment Video
Updated: Mar 18, 2026

Tissue Preparation Techniques for Contrast-Enhanced Micro Computed Tomography Imaging of Large Mammalian Cardiac Models with Chronic Disease
Published on: February 8, 2022
Computed tomography of acute heart failure: A novel case and literature review
Insights
Computed tomography (CT) reveals specific contrast imaging findings in critically ill patients with cardiac arrest. A new finding, renal venointerstitial reflux, is described alongside known patterns of vena cava and hepatic contrast reflux.
Area of Science:
- Radiology
- Cardiovascular Imaging
- Medical Imaging
Background:
- Computed tomography (CT) is a widely used diagnostic imaging modality across diverse patient populations, from healthy individuals to the critically ill.
- Contrast-enhanced CT plays a crucial role in evaluating patients experiencing cardiac arrest or impending cardiac failure.
- Existing literature documents characteristic imaging findings in this patient subset, including inferior vena cava and hepatic parenchymal contrast abnormalities.
Observation:
- Patients undergoing contrast-enhanced CT for cardiac arrest or failure exhibit specific patterns of contrast material.
- These patterns include reflux, pooling, and dependent layering of contrast within the inferior vena cava and hepatic parenchyma.
- A novel observation in a case study involves renal venointerstitial reflux in conjunction with these known findings.
Findings:
- The study reviews established contrast CT imaging findings in patients with cardiac compromise.
- It highlights inferior vena cava and hepatic parenchymal contrast reflux, pooling, and layering as documented phenomena.
- The primary finding is the identification and description of renal venointerstitial reflux, a previously undocumented observation in this clinical context.
Implications:
- The recognition of these contrast patterns, including the newly described renal venointerstitial reflux, can aid in the diagnosis and management of critically ill patients.
- This imaging information may offer insights into the hemodynamic changes and physiological status of patients with severe cardiac dysfunction.
- Further research into the clinical significance and prognostic value of these specific CT findings is warranted.
Abstract:
Computed tomography (CT) is used in patients whose conditions span the gamut from healthy to critically ill. In the specific subset of patients with cardiac arrest or imminent cardiac failure who receive contrast-enhanced CT, extant literature illustrates a set of imaging findings that include inferior vena cava and hepatic parenchymal contrast reflux, pooling, and layering in a dependent fashion. We review the literature and present a case in which these findings are demonstrated along with renal venointerstitial reflux, a finding that has not been previously described.
More Related Videos
11:09High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
08:13In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Related Concept Videos
Imaging Studies for Cardiovascular System V: CT
Acute Coronary Syndrome III: Diagnostic Studies
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies III: Computed Tomography
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT