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Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

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Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
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Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

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Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
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Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

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Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
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Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

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Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
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Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Myocarditis I: Introduction01:21

Myocarditis I: Introduction

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Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
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Infective endocarditis caused by Streptococcus tigurinus-like organisms.

O Peuchant1, G Wirth2, R Tixier3

  • 1Université de Bordeaux, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, France; INRA, USC EA 3671 Mycoplasmal and Chlamydial Infections in Humans, France; Centre Hospitalier Universitaire de Bordeaux, Laboratoire de Bactériologie, France.

New Microbes and New Infections
|July 14, 2016
PubMed
Summary
This summary is machine-generated.

Accurate identification of Streptococcus species causing infective endocarditis is difficult. This study identifies Streptococcus tigurinus-like organisms using 16S ribosomal RNA gene sequencing and shetA gene phylogeny.

Keywords:
16S rRNAPCRStreptococcus tigurinusendocarditisshet A gene

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Genetics

Background:

  • Streptococcus species are significant pathogens in infective endocarditis.
  • Accurate species identification is crucial for effective treatment but often challenging.
  • Novel Streptococcus species require reliable diagnostic methods.

Purpose of the Study:

  • To report and characterize two cases of infective endocarditis caused by Streptococcus tigurinus-like organisms.
  • To evaluate the utility of 16S ribosomal RNA gene sequencing and shetA gene phylogeny for identifying these challenging pathogens.
  • To contribute to the understanding of Streptococcus species diversity in endocarditis.

Main Methods:

  • Case reporting of two patients with infective endocarditis.
  • Identification of causative organisms using 16S ribosomal RNA gene sequencing.
  • Phylogenetic analysis of the shetA gene for species confirmation.
  • Clinical data review and microbiological investigation.

Main Results:

  • Two cases of infective endocarditis were successfully attributed to Streptococcus tigurinus-like organisms.
  • 16S ribosomal RNA gene sequencing provided initial identification.
  • Phylogenetic analysis of the shetA gene confirmed the species identification.
  • The diagnostic approach proved effective for these challenging isolates.

Conclusions:

  • Streptococcus tigurinus-like organisms can cause infective endocarditis.
  • A combination of 16S ribosomal RNA gene sequencing and shetA gene phylogeny is a robust method for identifying these bacteria.
  • Improved diagnostic strategies are essential for managing infective endocarditis caused by difficult-to-identify Streptococcus species.