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Data on cytochrome c oxidase assembly in mice and human fibroblasts or tissues induced by SURF1 defect
Nikola Kovářová1, Petr Pecina1, Hana Nůsková1
1Institute of Physiology of the Czech Academy of Sciences, Vídeňská 1083, Prague, Czech Republic.
Abstract:
This paper describes data related to a research article entitled "Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects" [1]. This paper includes data of the quantitative analysis of individual forms of respiratory chain complexes I, III and IV present in SURF1 knockout (SURF1 (-/-) ) and control (SURF1 (+/+) ) mouse fibroblasts and tissues and in fibroblasts of human control and patients with SURF1 gene mutation. Also it includes data demonstrating response of complex IV, cytochrome c oxidase (COX), to reversible inhibition of mitochondrial translation in SURF1 (-/-) mouse and SURF1 patient fibroblast cell lines.
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