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Label-free Single Molecule Detection Using Microtoroid Optical Resonators
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Integrated label-free optical biochemical sensor with a large measurement range based on an angular grating-microring
Applied Optics
|July 14, 2016
Summary
This study introduces a novel photonic-integrated optical biochemical sensor using microring resonators and angular gratings. This design enhances measurement range for biomedical sensing applications.
Area of Science:
- Photonics
- Biomedical Sensing
- Optical Engineering
Background:
- Microring resonators are sensitive but limited by free spectral range.
- Angular gratings offer potential for enhanced measurement capabilities.
- Integrated photonics provides a platform for miniaturized sensors.
Purpose of the Study:
- To design and investigate a photonic-integrated optical biochemical sensor.
- To enhance the measurement range of microring resonator-based sensors.
- To achieve high sensitivity and low detection limits for biomedical applications.
Main Methods:
- Designing a sensor combining a microring resonator and angular gratings.
- Utilizing silicon-on-insulator (SOI) waveguide technology.
- Optimizing key structural parameters for favorable transmission properties.
Main Results:
- Achieved a high-quality factor > 1.03×10^5.
- Demonstrated concentration sensitivity > 95.27 pm/% for biochemical bulk sensing.
- Obtained a detection limit < 0.329% and an ultra-large measurement range of 50.2 nm.
Conclusions:
- The integrated microring resonator and angular grating design significantly expands the measurement range.
- This sensor architecture is suitable for ultra-large range liquid and gas biomedical sensing.
- The optimized sensor meets requirements for high sensitivity and low detection limits.
