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Key Developments for Partial Coherence Biometry and Optical Coherence Tomography in the Human Eye Made in Vienna
Christoph K Hitzenberger1, Wolfgang Drexler1, Rainer A Leitgeb1
1Center for Medical Physics and Biomedical Engineering Medical University of Vienna, Vienna, Austria.
Investigative Ophthalmology & Visual Science
|July 14, 2016
Summary
Optical biometry and optical coherence tomography (OCT) have seen major advancements. Fourier domain OCT and partial coherence interferometry biometry are now gold standards in ophthalmology.
Area of Science:
- Ophthalmic technology
- Biomedical optics
Background:
- Partial coherence interferometry (PCI) technology was developed in the 1980s.
- Fourier domain (FD) OCT offers superior sensitivity over time domain OCT.
- Advancements include ultrahigh-resolution, deep-penetration (1050 nm), Doppler OCT, polarization-sensitive OCT, and adaptive optics OCT.
Purpose of the Study:
- To outline key developments in optical biometry and OCT for ophthalmic applications.
- Highlight contributions from a pioneering research group.
Main Methods:
- Utilized partial coherence interferometry (PCI) for optical biometry.
- Developed and refined Fourier domain Optical Coherence Tomography (FD-OCT).
- Explored advanced OCT techniques including ultrahigh-resolution, deep-penetration, Doppler, polarization-sensitive, and adaptive optics.
Main Results:
- PCI biometry is crucial for cataract surgery and intraocular lens research.
- FD-OCT is essential for ocular and retinal diagnostics.
- 1050 nm OCT enhances penetration into deeper ocular tissues like the choroid.
Conclusions:
- The Vienna research group's work established PCI biometry as a gold standard.
- FD-OCT has become a gold standard for ophthalmic diagnostics.
