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Related Concept Videos

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Related Experiment Video

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Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
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Pediatric Optical Coherence Tomography in Clinical Practice-Recent Progress.

Helena Lee1, Frank A Proudlock2, Irene Gottlob2

  • 1Clinical and Experimental Sciences Faculty of Medicine, University of Southampton, Southampton, United Kingdom 2University of Leicester Ulverscroft Eye Unit, Leicester, United Kingdom.

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|July 14, 2016
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This summary is machine-generated.

Handheld spectral-domain optical coherence tomography (HH-SDOCT) is a valuable tool for diagnosing and managing pediatric eye conditions. This technology offers new insights into retinal and optic nerve development and disease in children.

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Pediatrics

Background:

  • Optical coherence tomography (OCT) has transformed adult eye care.
  • Pediatric ophthalmology previously lacked advanced OCT capabilities.
  • Handheld spectral-domain OCT (HH-SDOCT) now bridges this gap for children.

Purpose of the Study:

  • To review the diverse applications of OCT imaging in pediatric ophthalmology.
  • To highlight the unique considerations for pediatric OCT interpretation.
  • To showcase the diagnostic and monitoring utility of HH-SDOCT in young patients.

Main Methods:

  • Literature review of existing studies on HH-SDOCT in pediatric ophthalmology.
  • Analysis of adaptations required for pediatric OCT acquisition and interpretation.
  • Synthesis of findings on HH-SDOCT's role in various pediatric eye conditions.

Main Results:

  • HH-SDOCT aids in diagnosing retinopathy of prematurity (ROP) and nonaccidental injury (NAI).
  • It streamlines diagnosis for infantile nystagmus, retinal dystrophies, and degenerations.
  • HH-SDOCT assists in differentiating pediatric intraocular tumors and monitoring optic nerve pathologies like glaucoma and optic nerve hypoplasia.

Conclusions:

  • HH-SDOCT provides novel insights into pediatric retinal and optic nerve disease progression.
  • In vivo OCT studies reveal ongoing retinal development in conditions like achromatopsia and albinism.
  • Early intervention targeting retinal development may optimize visual function in pediatric eye diseases.