Reversible renal failure associated with ibuprofen in a child. A case report

The clinical presentation and management of a young boy with acute non-oliguric renal failure associated with a nonsteroidal anti-inflammatory drug (NSAID), ibuprofen, prescribed for the relief of pain is described. Deterioration of renal function developed unexpectedly but fortunately withdrawal of the drug and appropriate management resulted in spontaneous recovery. All NSAIDs have the ability to interfere with renal function and their administration should probably be avoided in children with pre-existing dehydration or with conditions that predispose to an increased risk of renal insufficiency.