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Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
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Growth of Cartilage and Bone Tissue01:27

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Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...
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Changes in the Appendicular Skeleton with Age01:09

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The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
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Bone Formation by Endochondral Ossification01:24

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Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
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Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

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Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
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Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
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Related Experiment Video

Updated: Mar 18, 2026

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies
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The Biomechanical Basis of Growth Plate Injuries.

D P Speer, J K Braun

    The Physician and Sportsmedicine
    |July 14, 2016
    PubMed
    Summary

    Children face a high risk of growth plate injuries from sports and recreational activities. This study highlights the prevalence and discusses prevention and diagnosis of these common childhood injuries.

    Area of Science:

    • Pediatric Orthopedics
    • Sports Medicine
    • Childhood Injury Prevention

    Background:

    • Growth plate injuries are a significant concern in pediatric patients.
    • Previous research may have underestimated the incidence of these injuries.
    • Understanding the biomechanics of growth plate injuries is crucial for effective management.

    Purpose of the Study:

    • To determine the incidence of growth plate injuries in children.
    • To identify common activities associated with these injuries.
    • To review anatomical and biomechanical factors, diagnosis, and prevention strategies.

    Main Methods:

    • Retrospective review of 134 consecutive growth plate injuries at a single institution over six years.
    • Analysis of injury mechanisms, including sports and recreational activities.

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    Related Experiment Videos

    Last Updated: Mar 18, 2026

    A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies
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  • Literature review of anatomical, biomechanical, diagnostic, and preventive aspects.

    • Main Results:

    • Growth plate injuries are more common in children than previously reported.
    • Team sports accounted for 22% of injuries.
    • Recreational activities like skateboarding and bicycling contributed to 20% of injuries.

    Conclusions:

    • Children are at substantial risk for growth plate injuries.
    • A comprehensive approach to prevention and diagnosis is essential.
    • Further research into biomechanical factors can inform injury reduction strategies.