Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation02:47

Alkynes to Aldehydes and Ketones: Hydroboration-Oxidation

21.7K
Introduction
One of the convenient methods for the preparation of aldehydes and ketones is via hydration of alkynes. Hydroboration-oxidation of alkynes is an indirect hydration reaction in which an alkyne is treated with borane followed by oxidation with alkaline peroxide to form an enol that rapidly converts into an aldehyde or a ketone. Terminal alkynes form aldehydes, whereas internal alkynes give ketones as the final product.
21.7K
Hydroboration-Oxidation of Alkenes03:08

Hydroboration-Oxidation of Alkenes

12.0K
In addition to the oxymercuration–demercuration method, which converts the alkenes to alcohols with Markovnikov orientation, a complementary hydroboration-oxidation method yields the anti-Markovnikov product. The hydroboration reaction, discovered in 1959 by H.C. Brown, involves the addition of a B–H bond of borane to an alkene giving an organoborane intermediate. The oxidation of this intermediate with basic hydrogen peroxide forms an alcohol.
12.0K
Organic Compounds03:02

Organic Compounds

58.4K
All living things are formed mostly of carbon compounds called organic compounds. The category of organic compounds includes both natural and synthetic compounds that contain carbon. Although a single, precise definition has yet to be identified by the chemistry community, most agree that a defining trait of organic molecules is the presence of carbon as the principal element, bonded to hydrogen and other carbon atoms. However, some carbon-containing compounds such as carbonates, cyanides, and...
58.4K
Alcohols from Carbonyl Compounds: Reduction02:23

Alcohols from Carbonyl Compounds: Reduction

13.0K
Reduction is a simple strategy to convert a carbonyl group to a hydroxyl group. The three major pathways to reduce carbonyls to alcohols are catalytic hydrogenation, hydride reduction, and borane reduction.
Catalytic hydrogenation is similar to the reduction of an alkene or alkyne by adding H2 across the pi bond in the presence of transition metal catalysts like Raney Ni, Pd–C, Pt, or Ru. Aldehydes and ketones can be reduced by this method, often under mild to moderate heat (25–100°C) and...
13.0K
Regioselectivity and Stereochemistry of Hydroboration02:36

Regioselectivity and Stereochemistry of Hydroboration

9.7K
A significant aspect of hydroboration–oxidation is the regio- and stereochemical outcome of the reaction.
Hydroboration proceeds in a concerted fashion with the attack of borane on the π bond, giving a cyclic four-centered transition state. The –BH2 group is bonded to the less substituted carbon and –H to the more substituted carbon. The concerted nature requires the simultaneous addition of –H and –BH2 across the same face of the alkene giving syn stereochemistry.
9.7K
Carboxylic Acids to Primary Alcohols: Hydride Reduction01:17

Carboxylic Acids to Primary Alcohols: Hydride Reduction

5.5K
Carboxylic acids, upon reaction with strong reducing agents such as lithium aluminum hydride followed by hydrolysis, undergo reduction to form primary alcohols.
5.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A need to know.

The Physician and sportsmedicine·2016
Same author

A need to know.

The Physician and sportsmedicine·2016
Same author

A need to know.

The Physician and sportsmedicine·2016
Same author

A need to know.

The Physician and sportsmedicine·2016
Same author

The Bassler Hypothesis: A Eulogy.

The Physician and sportsmedicine·2016
Same author

A need to know.

The Physician and sportsmedicine·2016
Same journal

Injury surveillance during the 2024 under 20s Men's European Field Lacrosse Championships.

The Physician and sportsmedicine·2026
Same journal

Understanding health insurance and the delay in care for partial meniscectomies: a comparison between public and private coverage.

The Physician and sportsmedicine·2026
Same journal

Injury incidence and risk factors in youth American football versus soccer: a national emergency department analysis.

The Physician and sportsmedicine·2026
Same journal

Links between concussion history, hypertension, and hypertension contributing factors among adolescent football athletes.

The Physician and sportsmedicine·2026
Same journal

Core muscle endurance and balance as predictors of lateral ankle sprain in adolescent team-sport athletes: a prospective cohort study.

The Physician and sportsmedicine·2026
Same journal

Impact of Achilles tendon rupture on performance and career outcomes in NFL players: a matched cohort study.

The Physician and sportsmedicine·2026
See all related articles

Related Experiment Video

Updated: Mar 18, 2026

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
10:44

Isolating Free Carbenes, their Mixed Dimers and Organic Radicals

Published on: April 19, 2019

11.8K

Burn Carbohydrates, Not Hydrocarbons

A J Siegel

    The Physician and Sportsmedicine
    |July 14, 2016
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Biomass Conversion to Produce Hydrocarbon Liquid Fuel Via Hot-vapor Filtered Fast Pyrolysis and Catalytic Hydrotreating
    11:28

    Biomass Conversion to Produce Hydrocarbon Liquid Fuel Via Hot-vapor Filtered Fast Pyrolysis and Catalytic Hydrotreating

    Published on: December 25, 2016

    27.4K
    A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments
    20:28

    A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments

    Published on: October 2, 2012

    14.7K

    Related Experiment Videos

    Last Updated: Mar 18, 2026

    Isolating Free Carbenes, their Mixed Dimers and Organic Radicals
    10:44

    Isolating Free Carbenes, their Mixed Dimers and Organic Radicals

    Published on: April 19, 2019

    11.8K
    Biomass Conversion to Produce Hydrocarbon Liquid Fuel Via Hot-vapor Filtered Fast Pyrolysis and Catalytic Hydrotreating
    11:28

    Biomass Conversion to Produce Hydrocarbon Liquid Fuel Via Hot-vapor Filtered Fast Pyrolysis and Catalytic Hydrotreating

    Published on: December 25, 2016

    27.4K
    A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments
    20:28

    A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments

    Published on: October 2, 2012

    14.7K