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Updated: Mar 17, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

20.8K

Multimodality assessment of upper airway obstruction in children with persistent obstructive sleep apnea after

Christopher Clark1,2, Seckin O Ulualp2

  • 1Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, U.S.A.

The Laryngoscope
|July 15, 2016
PubMed

Insights

Cine MRI and drug-induced sleep endoscopy (DISE) largely agree on identifying upper airway obstruction (UAO) sites in children with persistent obstructive sleep apnea (OSA) after surgery. Further research is needed to assess their accuracy.

Area of Science:

  • Pediatric Otolaryngology
  • Sleep Medicine
  • Diagnostic Imaging

Background:

  • Children with obstructive sleep apnea (OSA) often have multiple sites of upper airway obstruction (UAO).
  • Various techniques exist to evaluate UAO, but their comparative efficacy in specific pediatric populations is not fully established.
  • Persistent OSA after adenotonsillectomy (AT) in children necessitates accurate identification of UAO.

Purpose of the Study:

  • To compare the findings of cine magnetic resonance imaging (MRI) and drug-induced sleep endoscopy (DISE).
  • To evaluate the utility of cine MRI and DISE in identifying sites of UAO in children with persistent OSA post-adenotonsillectomy (AT).

Main Methods:

  • Retrospective chart review of children who underwent both DISE and cine MRI.
  • Data collected included demographics, medical history, BMI, polysomnography, and findings from both diagnostic procedures.
  • Comparison of UAO sites identified by cine MRI and DISE.

Main Results:

  • Fifteen children (7-18 years) with persistent OSA post-AT were analyzed.
  • Cine MRI and DISE identified the same UAO site in 10 patients (9 with single tongue obstruction, 1 with multiple sites).
  • DISE detected additional UAO sites in 3 patients, while cine MRI detected additional sites in 1 patient; one patient had differing findings.

Conclusions:

  • Cine MRI and DISE are largely concordant in documenting single and multiple UAO sites in children with persistent OSA post-AT.
  • The findings suggest similarity in the majority of cases evaluated.
  • Further investigation into the sensitivity and specificity of both cine MRI and DISE for detecting pediatric UAO is warranted.
Abstract

Keywords:
Magnetic resonance imagingchildrendrug-induced sleep endoscopyobstructive sleep apneatonsillectomy and adenoidectomy

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