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Published on: September 27, 2024
Gastric Cancer: Nanoparticles as Tools to Improve Treatment Efficacy
Ariel R Guerrero, Felipe Oyarzun-Ampuero1, Natalia Hassan
1Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile. Santos Dumont 964, Independencia, Santiago, Chile.
Abstract:
In recent years, advances in nanotechnology have raised the specter of developing effective agents for the treatment of high-impact diseases, like gastric cancer, which remains one of the major causes of cancer deaths worldwide. This article reviews advances in the treatment of this pathology using several types of nanoparticles. First, we start with an overview of gastric cancer, its prevention, detection and the available treatments. Then, we discuss nanotechnology-based novel strategies using polymeric nanosystems, nanovesicular systems and inorganic nanoparticles. All of these systems are being evaluated in the perspective of improving the targeting of anticancer drugs and reducing their negative side effects.
Insights
Nanotechnology offers new hope for treating gastric cancer, a leading cause of cancer deaths. This review explores nanoparticle-based strategies to improve drug targeting and reduce side effects for better gastric cancer treatment.
Area of Science:
- Oncology
- Nanotechnology
- Materials Science
Background:
- Gastric cancer is a significant global health challenge, responsible for numerous cancer-related deaths worldwide.
- Current treatment options for gastric cancer have limitations, necessitating the exploration of novel therapeutic approaches.
Purpose of the Study:
- To review recent advances in nanotechnology for gastric cancer treatment.
- To discuss various nanoparticle systems being investigated for improved drug delivery and reduced toxicity.
Main Methods:
- Review of current literature on nanotechnology applications in gastric cancer therapy.
- Analysis of polymeric nanosystems, nanovesicular systems, and inorganic nanoparticles for drug delivery.
Main Results:
- Nanoparticle-based strategies show promise in enhancing the targeted delivery of anticancer drugs.
- These advanced systems have the potential to minimize adverse side effects associated with conventional chemotherapy.
Conclusions:
- Nanotechnology presents a promising frontier for developing more effective and safer treatments for gastric cancer.
- Further research into nanoparticle-based systems could revolutionize gastric cancer therapy.
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