Related Experiment Video
Updated: Mar 17, 2026

12:38
4D Multimodality Imaging of Citrobacter rodentium Infections in Mice
Published on: August 13, 2013
13.6K
Musculoskeletal infections associated with Citrobacter koseri.
T A Kwaees1, Z Hakim1, C Weerasinghe1
1Blackpool Teaching Hospitals NHS Foundation Trust , UK.
Annals of the Royal College of Surgeons of England
|July 15, 2016
Summary
Citrobacter koseri rarely causes musculoskeletal infections, but can lead to aggressive septic arthritis. Prompt diagnosis and treatment with antibiotics and surgery are crucial for recovery.
Area of Science:
- Microbiology
- Infectious Diseases
- Orthopedics
Background:
- Citrobacter koseri is a known pathogen causing central nervous system infections in children.
- Musculoskeletal infections due to C. koseri are exceptionally rare, with only 14 cases previously documented.
Observation:
- This report details the first documented case of C. koseri-induced septic arthritis of the knee.
- A literature review identified 14 cases of C. koseri musculoskeletal infections, with 5 linked to surgery and 5 involving septic joints.
Findings:
- Most C. koseri musculoskeletal infections necessitate surgical intervention.
- Prolonged antibiotic therapy, particularly newer generation beta-lactams and cephalosporins, led to successful outcomes in all reviewed cases.
Implications:
- C. koseri infections can complicate orthopedic procedures, presenting aggressively and posing diagnostic challenges.
- Early recognition, appropriate antibiotic selection, and timely surgical management are key for effective treatment of C. koseri musculoskeletal infections.
Related Concept Videos
Urinary Tract Infection I: Introduction
932
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
932
Urinary Tract Infection II: Pathophysiology
1.0K
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
1.0K
Bacterial Phylum Spirochaetes
1.1K
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
1.1K
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
6.4K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
6.4K
Urine Studies II: Urine Culture and Sensitivity Test
1.9K
A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
1.9K
Skin Diseases and Disorders
6.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.1K

