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Parasites and immunotherapy: with or against?
Hossein Yousofi Darani1, Morteza Yousefi2, Marzieh Safari3
1Cancer Prevention Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Summary
Immunotherapy uses antibodies or antigens to treat diseases like infections and cancer. This review explores its use in parasitic infections and employing parasites to treat other conditions.
Area of Science:
- Immunology and Parasitology
- Therapeutic Strategies
Background:
- Immunotherapy involves administering antibodies or antigens to manage diseases.
- It is applied across diverse conditions including infectious diseases, autoimmune disorders, cancers, and allergies.
Purpose of the Study:
- To review immunotherapy strategies for common parasitic infections.
- To examine the use of parasites or parasite antigens in immunotherapy for non-parasitic diseases like cancer, asthma, and multiple sclerosis.
Main Methods:
- Literature review of existing studies on immunotherapy.
- Analysis of successful and unsuccessful immunotherapeutic approaches in parasitic infections.
- Exploration of parasite-derived immunotherapy for other diseases.
Main Results:
- Immunotherapy has shown varied success in treating parasitic infections.
- Parasites and their antigens are being investigated as novel immunotherapeutic agents for cancer, asthma, and multiple sclerosis.
Conclusions:
- Immunotherapy offers a versatile approach to treating parasitic infections.
- Parasite-derived immunotherapy presents a promising, albeit complex, avenue for managing non-parasitic diseases.
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