Transoral CO2 Laser Microsurgery Outcomes for Early Glottic Carcinomas T1-T2

Area of Science:

• Otolaryngology
• Oncologic Surgery
• Laryngeal Cancer Research

Background:

• Transoral laser microsurgery (TLM) is an established technique in larynx oncology for treating tumors of the glottis, supraglottis, and hypopharynx.
• TLM offers advantages such as limited resections, reduced need for tracheostomies, and use of nasogastric tubes.
• Its oncological benefits are comparable to open surgery for selected early and advanced stage tumors.

Purpose of the Study:

• To review the oncologic outcomes of glottic tumors treated with Transoral laser microsurgery (TLM).

Main Methods:

• Retrospective analysis of 58 previously untreated patients diagnosed with squamous cell carcinoma of the glottis (T1a, T1b, T2).
• Data collected from a tertiary university hospital.
• Endpoints included local control, overall survival, disease-specific survival, and larynx preservation rate.

Main Results:

• The study included 58 patients (98.3% male, mean age 65.5 years).
• Tumor stages were T1a (n=30), T1b (n=11), and T2 (n=17).
• Three-year rates were: overall survival 89.7%, disease-specific survival 96.5%, local control 98.3%, and organ preservation 98.3%.

Conclusions:

• Transoral laser microsurgery (TLM) is a safe and effective treatment for glottic carcinomas.
• TLM is associated with decreased patient morbidity.
• High rates of local control, overall survival, disease-specific survival, and organ preservation were achieved.