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Transmission Electron Microscopy

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In 1931, physicist Ernst Ruska—building on the idea that magnetic fields can direct an electron beam just as lenses can direct a beam of light in an optical microscope—developed the first prototype of the electron microscope. This development led to the development of the field of electron microscopy. In the transmission electron microscope (TEM), electrons are produced by a hot tungsten element and accelerated by a potential difference in an electron gun, which gives them up to 400...

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Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers

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Published on: August 31, 2021

Virtual Environment for Manipulating Microscopic Particles With Optical Tweezers.

Yong-Gu Lee¹, Kevin W Lyons¹, Thomas W LeBrun¹

¹National Institute of Standards and Technology, Gaithersburg, MD 20899-0001.

Journal of Research of the National Institute of Standards and Technology

|July 15, 2016

Summary

This summary is machine-generated.

This study introduces a virtual reality interface for nanoscale manipulation, enabling intuitive control of laser-trapped particles. Users can naturally steer particles, with haptic feedback guiding movements within physical limits.

Keywords:

nanoscale assembly nanotechnology optical tweezers virtual reality

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Last Updated: Mar 17, 2026

Direct Force Measurements of Subcellular Mechanics in Confinement using Optical Tweezers

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Published on: August 31, 2021

Use of Dual Optical Tweezers and Microfluidics for Single-Molecule Studies

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Optical Trapping of Nanoparticles

Optical Trapping of Nanoparticles

Published on: January 15, 2013

Area of Science:

Physics
Engineering
Computer Science

Background:

Nanoscale manipulation is crucial for various scientific and technological applications.
Existing interfaces for nanoscale devices can be complex and lack intuitiveness.

Purpose of the Study:

To develop an intuitive virtual reality (VR) interface for a nanoscale manipulation device.
To enable natural user control over the trapping and repositioning of nano-to-microscopic particles.

Main Methods:

Utilized virtual reality techniques for interface design.
Employed optical methods with focused laser light for particle trapping and manipulation.
Simulated underlying physics using Lagrange mechanics.
Implemented a novel control method with haptic feedback.

Main Results:

Demonstrated an intuitive user interface for nanoscale manipulation.
Successfully trapped and repositioned nano-to-microscopic particles using laser light.
Developed a control system allowing users to 'grab' and steer particles naturally.
Integrated haptic feedback to ensure physically constrained motion.

Conclusions:

Virtual reality provides an intuitive and effective interface for nanoscale manipulation.
The developed system allows for precise control of laser-trapped particles.
Haptic feedback enhances the usability and safety of nanoscale manipulation through VR.