Placental Mechanics in the Zika-Microcephaly Relationship
Jennifer J Adibi1, Yaqi Zhao2, Abigail R Cartus2
1Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Cell Host & Microbe
|July 15, 2016
Abstract:
How the Zika virus (ZIKV) accesses the embryo remains unknown. In this issue, Quicke et al. (2016) use an in vitro model of the human placenta to show that placental macrophages are more permissive to ZIKV infection than trophoblasts, which may be refractory to infection (Bayer et al., 2016).
