Related Experiment Video
Updated: Mar 17, 2026

Combining Fluidic Devices with Microscopy and Flow Cytometry to Study Microbial Transport in Porous Media Across Spatial Scales
Published on: November 25, 2020
Leveraging percolation theory to single out influential spreaders in networks
Filippo Radicchi1, Claudio Castellano2
1Center for Complex Networks and Systems Research, School of Informatics and Computing, Indiana University, Bloomington, Indiana 47408, USA.
Abstract:
Among the consequences of the disordered interaction topology underlying many social, technological, and biological systems, a particularly important one is that some nodes, just because of their position in the network, may have a disproportionate effect on dynamical processes mediated by the complex interaction pattern. For example, the early adoption of a commercial product by an opinion leader in a social network may change its fate or just a few superspreaders may determine the virality of a meme in social media. Despite many recent efforts, the formulation of an accurate method to optimally identify influential nodes in complex network topologies remains an unsolved challenge. Here, we present the exact solution of the problem for the specific, but highly relevant, case of the susceptible-infected-removed (SIR) model for epidemic spreading at criticality. By exploiting the mapping between bond percolation and the static properties of the SIR model, we prove that the recently introduced nonbacktracking centrality is the optimal criterion for the identification of influential spreaders in locally tree-like networks at criticality. By means of simulations on synthetic networks and on a very extensive set of real-world networks, we show that the nonbacktracking centrality is a highly reliable metric to identify top influential spreaders also in generic graphs not embedded in space and for noncritical spreading.
Related Concept Videos
Theories of Dissolution: Diffusion Layer Model
This process starts with a thin layer, saturated with the drug, forming at the interface between the solid and liquid. The solute then diffuses from this layer into the main solution. The Noyes-Whitney equation suggests that the rate of dissolution relies on the diffusion...
Diffusion
Diffusion
Passive Diffusion: Overview and Kinetics
When administered orally, drugs establish a substantial concentration gradient between the gastrointestinal (GI) lumen and the bloodstream, expediting...
Gene Flow
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...

