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Apparent Life-Threatening Events: Helping Infants Help Themselves
Alessandro Vigo, Roberto Balagna1, Luca Brazzi
1Department of Anaesthesia and Intensive Care, Città della Salute e della Scienza.
Insights
Apparent life-threatening events (ALTE) in infants are alarming but typically self-limiting. Simple tactile stimulation (TS) often resolves these episodes, with emergency services prioritizing TS before considering cardiopulmonary resuscitation.
Area of Science:
- Pediatrics
- Emergency Medicine
- Neonatology
Background:
- Apparent life-threatening events (ALTE) are sudden, alarming episodes in infants.
- Understanding parental response and emergency service (ES) intervention is crucial for infant outcomes.
Purpose of the Study:
- Evaluate home-based ES intervention for ALTE.
- Assess parental behavior preceding ES intervention.
- Determine infant outcomes at 6-month follow-up.
Main Methods:
- Retrospective study of infants under 12 months with ALTE (2005-2014).
- Defined tactile stimulation (TS) and cardiopulmonary resuscitation (CPR) per AHA guidelines.
- Analyzed ES response times and patient condition upon examination and at follow-up.
Main Results:
- 188 infants eligible; 178 received ES intervention.
- All infants received parental TS before ES arrival.
- No infant experienced subsequent cardiopulmonary arrest or adverse neurological outcomes; 6 were diagnosed with epilepsy.
- Capillary blood gas alterations found in 26% of tested infants.
Conclusions:
- ALTE is generally self-limiting, often resolving with spontaneous recovery or TS.
- ES should utilize TS to elicit physiological responses before considering CPR for ALTE.
- Infant outcomes following ALTE are typically favorable.
Objectives:
Apparent life-threatening event (ALTE) refers to a constellation of unexpected events suddenly occurring in infants that extremely alarm the observers. The objectives of this study were to evaluate 1) intervention of Emergency Service (ES) at home, 2) parental behavior before ES intervention, 3) patients' outcome at follow-up of a minimum of 6 months.
Methods:
Retrospective study of infants younger than 12 months whose parents called ES and were evaluated for ALTE from 2005 to 2014. Tactile stimulation (TS) was defined as any maneuver performed by parents or ES staff aimed at rescuing patients without cardiopulmonary resuscitation attempts. Cardiopulmonary resuscitation was defined according to American Heart Association Guidelines 2010.
Results:
One hundred eighty-eight patients were eligible. Emergency Service provided intervention for 178 infants (10 were assisted only by phone). All patients received TS by parents before ES arrival. Mean time for ES to reach patient location was 15 ± 10 minutes. On examination, 136 patients (76.5%) seemed normal and 42 symptomatic. One hundred sixty-three patients were brought to the emergency department where 23 patients were found symptomatic. One hundred six of 163 patients underwent capillary blood gas determination and, in 28 (26%) of 106, alterations were found. No infant had subsequent cardiopulmonary arrest or clinically evident adverse neurological outcome. Six were found to be epileptic. No infant died during the episode or during follow-up.
Conclusions:
Our findings suggest that ALTE is an alarming but self-limiting phenomenon that can be resolved either spontaneously or by simple TS in most cases. Emergency Service should solicit patients' physiological responses through TS first while considering a cardiopulmonary resuscitation maneuver.
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