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RNA polymerase I-Rrn3 complex at 4.8 Å resolution.

Christoph Engel1, Jürgen Plitzko2, Patrick Cramer1

  • 1Max Planck Institute for Biophysical Chemistry, Department of Molecular Biology, Am Fassberg 11, 37077 Göttingen, Germany.

Nature Communications
|July 16, 2016
PubMed
Summary

The initiation factor Rrn3 is essential for ribosomal DNA transcription by RNA polymerase I (Pol I). We determined the cryo-electron microscopy structure of the Pol I-Rrn3 complex, revealing its mechanism for activating Pol I for transcription initiation.

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