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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Related Experiment Video

Updated: Mar 17, 2026

Deep Brain Stimulation with Simultaneous fMRI in Rodents

Deep Brain Stimulation with Simultaneous fMRI in Rodents

Published on: February 15, 2014

Optimized, Minimal Specific Absorption Rate MRI for High-Resolution Imaging in Patients with Implanted Deep Brain

A M Franceschi¹, G C Wiggins¹, A Y Mogilner²

¹From the Departments of Radiology (A.M.F., G.C.W., T.S., S.C., Y.W.L.).

AJNR. American Journal of Neuroradiology

|July 16, 2016

Summary

This summary is machine-generated.

High-quality brain MRI is now feasible in patients with deep brain stimulators. This optimized protocol ensures safety and provides adequate imaging for surgical planning, overcoming previous challenges.

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Area of Science:

Neurology
Radiology
Neurosurgery

Background:

Deep brain stimulator (DBS) implantation presents challenges for high-resolution brain MRI due to safety concerns.
Previous concerns have limited MRI use in patients with implanted DBS devices.

Purpose of the Study:

To present a practical clinical protocol for obtaining high-resolution brain MRI in patients with existing DBS implants.
To demonstrate the feasibility of achieving presurgical quality imaging for staged DBS insertion.

Main Methods:

Optimized a 1.5T MRI protocol to minimize specific absorption rate (SAR) while maintaining image quality for surgical planning.
Reviewed 29 patients with DBS implants who underwent MRI between 2012 and 2015.
Assessed image quality and artifacts qualitatively by a neuroradiologist and functional neurosurgeon.

Main Results:

Twenty-nine patients (Parkinson disease, dystonia, essential tremor) with DBS implants were successfully imaged.
No adverse events occurred during or after MRI scans.
Mild susceptibility artifacts were present but did not compromise overall image quality; all preoperative studies were adequate for guiding second DBS electrode placement.

Conclusions:

An optimized, low-SAR MR imaging protocol can safely acquire high-quality brain images in patients with DBS.
These images are sufficient for guiding subsequent deep brain stimulator placement.
This protocol addresses a significant challenge in neuroimaging for patients with neuromodulation devices.