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Manganese absorption from human milk, cow's milk, and infant formulas in humans
L Davidsson1, A Cederblad, B Lönnerdal
1Department of Clinical Nutrition, University of Gothenburg, Sahlgrenska Hospital, Göteborg, Sweden.
Abstract:
Manganese absorption from human milk, cow's milk, and infant formulas was studied in humans by using extrinsic labeling of the diets with manganese 54 or manganese 52 and whole-body retention measurements. The fractional manganese absorption from human milk (8.2% +/- 2.9%) was significantly different when compared with cow's milk (2.4% +/- 1.7%), soy formula (0.7% +/- 0.2%), and whey-preponderant cow's milk formula with 12 mg/L of iron (1.7% +/- 1.0%) and without iron fortification (2 mg/L of iron) (3.1% +/- 2.8%), while no significant difference was observed between a whey-preponderant cow's milk formula with 7 mg/L of iron (5.9% +/- 4.8%) and human milk. The total amount of absorbed manganese was significantly higher from the non--iron-fortified cow's milk formula (2 mg/L of iron) as compared with human milk, while no significant differences were observed for the other milks and formulas.
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