Periprocedural antithrombotic therapy during various types of percutaneous cardiovascular interventions

Area of Science:

• Cardiovascular Medicine
• Interventional Cardiology
• Thrombosis Management

Background:

• Percutaneous catheter-based interventions are vital in modern cardiology, enhancing patient quality of life and survival.
• These procedures involve foreign materials and endothelial damage, significantly increasing the risk of thrombotic complications.
• Antithrombotic therapy is essential during these interventions to mitigate clotting risks.

Purpose of the Study:

• To summarize current antithrombotic treatment strategies for percutaneous catheter-based interventions.
• To provide guidance on managing clotting and bleeding risks across various cardiovascular procedures.
• To highlight the variability in antithrombotic therapy based on procedural type, clinical setting, and patient comorbidities.

Main Methods:

• Review of current literature and guidelines on antithrombotic therapy in interventional cardiology.
• Synthesis of data pertaining to periprocedural antithrombotic management.
• Categorization of therapeutic approaches based on specific intervention types.

Main Results:

• Antithrombotic therapy is a standard requirement for percutaneous catheter interventions.
• The optimal antithrombotic regimen (dose, combination, duration) is procedure- and patient-specific.
• Management strategies must balance the prevention of thrombosis with the risk of bleeding.

Conclusions:

• Effective antithrombotic management is critical for the safety and success of percutaneous catheter interventions.
• Tailoring antithrombotic therapy to individual patient and procedural characteristics is paramount.
• This review provides a comprehensive overview of current practices for preventing thrombotic and bleeding complications.