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Medication Adherence Among Adolescents with Bipolar Disorder
Tina R Goldstein1, Megan Krantz1, John Merranko1
11 Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center , Pittsburgh, Pennsylvania.
Journal of Child and Adolescent Psychopharmacology
|July 16, 2016
Summary
Medication adherence is poor in adolescents with bipolar disorder (BP), with objective data showing over 40% of doses missed. Subjective reports overestimate adherence, highlighting the need for careful clinical attention to this issue.
Area of Science:
- Child and Adolescent Psychiatry
- Psychopharmacology
- Mental Health Research
Background:
- Adolescents with bipolar disorder (BP) often struggle with medication adherence.
- Accurate assessment of adherence is crucial for effective treatment management.
- Previous studies have relied heavily on subjective adherence measures.
Purpose of the Study:
- To investigate medication adherence rates in adolescents diagnosed with bipolar disorder.
- To identify factors associated with medication adherence using objective and subjective methods.
- To compare objective adherence data with self- and parent-reported adherence.
Main Methods:
- Recruited 21 adolescents with a primary BP diagnosis on psychotropic medication.
- Assessed self- and parent-reported adherence monthly for 6 months.
- Collected objective adherence data via electronic weekly pillboxes.
Main Results:
- Objective data revealed 41.5% of prescribed doses were missed over a 3-month follow-up.
- Subjective reports significantly overestimated actual medication adherence.
- Illness severity, cognitive difficulties, and dose timing were linked to poorer adherence.
Conclusions:
- Adolescents with bipolar disorder exhibit significant medication non-adherence.
- Subjective adherence reports are unreliable and overestimate compliance.
- Clinicians must prioritize objective adherence assessment for treatment decisions in pediatric BP.
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