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Updated: Mar 17, 2026

Characterization of Adipocyte-Derived Extracellular Vesicle Secretion Using a CD63-GFP Reporter Mouse Model In Vivo and In Vitro
Published on: December 5, 2025
[Relationship between Obesity, Adipokines and Systemic Lupus Erythematosus]
Tomas Urrego1, Gloria M Vásquez2, Jose A Gómez-Puerta2
1Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Abstract:
Obesity is a pro-inflammatory state characterized by phenotypic changes in macrophages, alterationson cytokines balance, and increasing expression of regulatory molecules of the immune system derived from adipocytes and adipose tissue macrophages - also known as adipokines. Currently, leptin, adiponectin and resistin are, among others, one of the most known adipokines. Theseadipokinesmight play a possible role in systemic lupus erythematosus pathogenesis, by promotingdifferent pro-inflammatory conditions. Adipokines represent a possible treatment target in patients with lupus.
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