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Updated: Mar 17, 2026

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Current Management in Sickle Cell Disease.

M Roberts-Harewood1, S C Davies1

  • 1a Haematology Department , Central Middlesex Hospital , Acton Lane, London NW10 7NS.

Hematology (Amsterdam, Netherlands)
|July 16, 2016
PubMed
Summary
This summary is machine-generated.

Sickle cell disease (SCD) is rising in the UK. This review covers SCD management, complications, and prognosis for clinicians, incorporating global research and clinical insights.

Keywords:
Sickle cell diseaseacute and chronic complicationsnovel therapies

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Area of Science:

  • Hematology
  • Internal Medicine
  • Genetics

Background:

  • The prevalence of sickle cell disease (SCD) in the UK is increasing.
  • Patient demographics are shifting, with a younger, more mobile population no longer exclusively attending specialist centers.
  • Clinician awareness of SCD, its complications, prognosis, and management is crucial.

Purpose of the Study:

  • To provide a comprehensive overview of current sickle cell disease management strategies.
  • To highlight the acute and chronic manifestations of SCD.
  • To integrate international advancements, clinical experience, and current research into SCD care.

Main Methods:

  • Literature review of current management practices for sickle cell disease.
  • Synthesis of international advances and research findings.
  • Incorporation of clinical anecdotes and expert opinion.

Main Results:

  • The review details the multifaceted nature of SCD management, addressing both acute and chronic aspects.
  • It emphasizes the need for broader clinician understanding beyond specialist centers.
  • International data and ongoing research are integrated to inform current practices.

Conclusions:

  • Effective management of sickle cell disease requires a comprehensive approach, considering its diverse manifestations and evolving patient population.
  • Continuous education and awareness among all clinicians are essential for optimal patient outcomes.
  • The integration of global research and clinical insights is vital for advancing SCD care in the UK.