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Updated: Mar 17, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Current Management in Sickle Cell Disease
M Roberts-Harewood1, S C Davies1
1a Haematology Department , Central Middlesex Hospital , Acton Lane, London NW10 7NS.
Abstract:
The number of people in the UK with sickle cell disease continues to rise. Therefore it becomes increasingly important for all clinicians to be cognisant of not only the disorder, but also its complications, prognosis, implications and management. Previously the majority of patients lived within urban areas and attended a few specialist centres, now the young, mobile population of patients are no longer confined to teaching hospitals. In the UK, few centres have experience of many patients but collectively patients' numbers are considerable. This review discusses our view of the current management of the acute and chronic manifestations of this disease, supplemented by international advances, anecdote and current research.
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