Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Exercise Stress Test01:26

Exercise Stress Test

1.7K
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
1.7K
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

1.1K
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
1.1K
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

4.9K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
4.9K
Exercise and Muscle Performance01:27

Exercise and Muscle Performance

2.9K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
2.9K
Relaxation of Skeletal Muscles01:29

Relaxation of Skeletal Muscles

6.6K
The period of muscle contraction primarily influences the duration of stimulation at the neuromuscular junction (NMJ), the presence of free calcium ions in the sarcoplasm, and the availability of energy or ATP to support contractions.
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open....
6.6K
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

384
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
384

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pharmacological treatment of CVD.

European heart journal. Cardiovascular pharmacotherapy·2022
Same author

Future of European Heart Journal Cardiovascular Pharmacotherapy.

European heart journal. Cardiovascular pharmacotherapy·2022
Same author

To treat or not to treat.

European heart journal. Cardiovascular pharmacotherapy·2022
Same author

The value of a new cardiac magnetic resonance imaging protocol in Myocardial Infarction with Non-obstructive Coronary Arteries (MINOCA) - a case-control study using historical controls from a previous study with similar inclusion criteria.

BMC cardiovascular disorders·2017
Same author

Gender differences in the effects of cardiovascular drugs.

European heart journal. Cardiovascular pharmacotherapy·2017
Same author

Cardiovascular pharmacotherapy.

International journal of cardiology·2016
Same journal

Beyond arrhythmias: Exploring heart failure in arrhythmogenic cardiomyopathy.

International journal of cardiology·2026
Same journal

Corrigendum to "First-in-human study of the K-Clipℱ transcatheter annular repair system for severe functional tricuspid regurgitation" [International Journal of Cardiology 390(2023) / IJCA 131174].

International journal of cardiology·2026
Same journal

From evidence to practice: Identifying candidates for semaglutide in chronic atherosclerotic disease.

International journal of cardiology·2026
Same journal

Impact of obesity on 1-year major adverse cardiac events after primary PCI for STEMI.

International journal of cardiology·2026
Same journal

Interpreting the athlete's ECG to prevent sudden death: An old tool in constant evolution.

International journal of cardiology·2026
Same journal

Left atrioventricular coupling index in transthyretin amyloid cardiomyopathy: Association with mortality.

International journal of cardiology·2026
See all related articles

Related Experiment Video

Updated: Mar 17, 2026

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training
07:40

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Published on: October 10, 2019

7.9K

Troponin and exercise.

T Gresslien1, S Agewall1

  • 1Department of Cardiology, Oslo University Hospital UllevĂ„l and Institute of Clinical Sciences, University of Oslo, Oslo, Norway.

International Journal of Cardiology
|July 16, 2016
PubMed
Summary
This summary is machine-generated.

Exercise can elevate cardiac troponin levels, a key marker for myocardial infarction. This review explores factors influencing troponin release post-exercise, suggesting a likely physiological mechanism.

Keywords:
ExerciseHealthy subjectsPhysiologicTroponin

More Related Videos

Induction and Assessment of Exertional Skeletal Muscle Damage in Humans
08:33

Induction and Assessment of Exertional Skeletal Muscle Damage in Humans

Published on: December 11, 2016

7.9K
Analysis of Cardiac Contractile Dysfunction and Ca2+ Transients in Rodent Myocytes
07:32

Analysis of Cardiac Contractile Dysfunction and Ca2+ Transients in Rodent Myocytes

Published on: May 25, 2022

1.9K

Related Experiment Videos

Last Updated: Mar 17, 2026

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training
07:40

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Published on: October 10, 2019

7.9K
Induction and Assessment of Exertional Skeletal Muscle Damage in Humans
08:33

Induction and Assessment of Exertional Skeletal Muscle Damage in Humans

Published on: December 11, 2016

7.9K
Analysis of Cardiac Contractile Dysfunction and Ca2+ Transients in Rodent Myocytes
07:32

Analysis of Cardiac Contractile Dysfunction and Ca2+ Transients in Rodent Myocytes

Published on: May 25, 2022

1.9K

Area of Science:

  • Cardiology
  • Exercise Physiology
  • Biomarkers

Background:

  • Cardiac troponins are primary diagnostic markers for myocardial infarction.
  • Elevated troponin levels are also observed following strenuous physical activity.
  • Previous studies show varied results and debate regarding the mechanisms of exercise-induced troponin release.

Purpose of the Study:

  • To review existing literature on exercise-induced increases in cardiac troponin.
  • To identify factors influencing troponin levels after physical exertion.
  • To elucidate the potential mechanisms behind troponin release during and after exercise.

Main Methods:

  • A comprehensive literature search was conducted using PubMed.
  • Additional relevant studies were identified through reference lists of initial findings.
  • A total of 145 studies were included in the review.

Main Results:

  • Troponin levels increased in 0-100% of subjects after prolonged or intermittent exercise.
  • Factors influencing troponin variation include exercise intensity, age, training status, sample timing, and assay methods.
  • The release pattern suggests a shift from the cardiomyocyte cytosolic compartment, potentially due to increased membrane permeability.

Conclusions:

  • Both intense and moderate exercise can lead to elevated cardiac troponin levels.
  • These findings must be considered in the clinical diagnosis of myocardial infarction in active individuals.
  • The most probable mechanism for post-exercise troponin elevation appears to be physiological.