[Chronic renal insufficiency in 22 children: diagnosis and evolution]

Clinical characteristics, evolution of growth, and glomerular rate were analysed in 22 patients, younger than 14 years, with chronic renal failure (glomerular filtration rate: 32.6 +/- 24.8 ml/min/1.73 m2, x +/- DS) with a minimal follow-up of 6 months (3.5 +/- 3.3 years). Recurrent urinary tract infections were the most common initial clinical features (27%) and obstructive uropathies constituted the most frequent etiology (41%). Renal failure progression rate, which was assessed by means of 1 to serum creatinine concentration ratio, was faster in the group of children with glomerulonephropaties. At the diagnosis, one out of 3 children had short stature. At the end of the follow-up time, the delay of growth did not significatively modified (-1.6 +/- 2.2 DS versus -2.1 +/- 1.2 DS, p greater than 0.05).